Mr Kade reported the missing animal to the Department of Primary Industries, which issued a note to residents of the estate and surrounding area on Friday warning that the government "has reason to believe there is an adult boa constrictor 'at large' in or around the Cascades Estate" after "a freshly shed snake skin was found at a property on Torumba Circuit".

Mr Kade said that, after he'd posted photos of the snake's skin on his Facebook page on Monday, he'd noticed people saying it could have been staged.

"It’s unlikely because there was actually slide marks on the concrete of the new house," he said.

"I’m thinking it’s just gone around to try and use the wood as some sort of abrasive material to get the skin off.

"He's definitely out there somewhere."

Mr Kade said the snake, an invasive species originating from South America, might have slithered into nearby bushland looking for food.

"We need to catch this snake if we possibly can, because it’s going to be quite destructive to the environment, too.

"The more people that know about it, the more eyes we have out there searching for this thing ... we obviously don't want it to fall into the wrong hands, either."

The letter circulated by the DPI noted that the snakes are prohibited in NSW outside zoos and are "a serious threat to wildlife and humans".

Anyone who sees the snake is warned not to approach it, but to photograph it if possible and take note of its location and/or where it goes, and call a snake handler or the NSW Department of Primary Industries as soon as possible.

A spokesperson for the department said biosecurity officers are working to locate and capture the snake.

"Boa constrictors are prohibited in NSW outside of zoos. They are a serious threat to wildlife and can be dangerous to humans. They can also carry exotic diseases which impact native animal populations," the spokesperson said.