Michael Buble has announced plans to "retire" from the music industry after admitting he no longer has the desire for fame following his son's cancer treatment.

The Canadian singer, who has won four Grammys and sold 75 million records, put his career on hold after finding out the five-year-old was diagnosed with liver cancer two years ago.

Noah, one of three children with wife of seven years, Argentinian model and actress Luisana Lopilato, is now in remission.

During an emotional "last interview", Buble opened up about the devastating impact Noah's illness had on the couple.

"My whole being's changed. My perception of life. I don't know if I can even get through this conversation without crying," he told The Daily Mail's Weekend Magazine.