Karl Stefanovic has launched an angry attack on Event Cinemas, accusing the cinema chain of a "grubby cash grab" for scheduling the release of Avengers: Infinity War on Anzac Day.

In a fiery piece to camera on Thursday morning's episode, the Today host urged cinemagoers to boycott the film's opening – set for Wednesday, a day earlier than the traditional Thursday release date – in order to keep the day "sacred".

"Event Cinemas bringing the release a day early smacks, to me, of a grubby cash grab," Stefanovic told viewers.

"Well, grab your cash somewhere else, exploit another day. Not on what I believe is the most important day on our nation’s calendar.

"How on earth are our kids supposed to breathe in the significance of Anzac Day, and the sacrifices, the great sacrifices, the impact on our nation, on our families?" he asked.