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The vehicle involved in the accident was one of Uber's many Volvo XC90s, which have been modified to accept Uber's autonomous hardware and software.
James Martin/CNETAn early morning crash between a pedestrian and an Uber self-driving car occurred in Tempe, Arizona, according to a report by TV station ABC15.
The crash is under investigation. It's not clear whether a driver was behind the wheel at the time.
On March 15, an Uber self-driving car in Pittsburgh was involved in a collision with another car. No injuries were reported, but both vehicles had serious damage. There was a safety driver in the Uber car at the time of this incident.
Uber did not immediately respond to a CNET request for comment.
This is a developing story.
Update, 10:36 p.m.: Indicated victim was a pedestrian, not a bicyclist as initially reported.