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Duterte's office has denied all accusations against him.
His supporters succeeded this week in dumping De Lima from her role on the inquiry, as Duterte continued to loudly defend his anti-drug war. On Tuesday he said he would tell EU officials who had criticized him "f**k you!"
If all that sounds crazy... we haven't even got started.
De Lima removed
Critics have described her removal as a "reprisal" for her role in investigating Duterte's anti-drug war, which has so far claimed hundreds of lives amid accusations of extrajudicial killings by police.
Following her ouster, De Lima herself has become the subject of an inquiry held by the House of Representatives, which is dominated by Duterte's allies.
Wait, Manny Pacquiao?
Yes, the former world champion boxer turned politician led the charge to unseat De Lima, saying the committee was being used to "pin down the administration."
"It's not our intention to stop the investigation," Pacquiao told CNN. "(But) it's about investigation, not singling out one person."
He said self-professed hitman Edgar Matobato would be invited to continue testifying, but argued that there were numerous "inconsistencies in his testimony" against Duterte.
Duterte vs. De Lima
"If I were De Lima, ladies and gentlemen, I'd hang myself," he said.
For her part, De Lima accused the President of throwing everything but the kitchen sink at her. "I'm still waiting for the sink."
What are the accusations against De Lima?
Flanked by armored police and granted immunity by Justice Secretary Vitaliano Aguirre, former drug dealer Herbert Colanggo told the House committee Tuesday that the New Bilibid Prison was turned into a "Little Las Vegas" during De Lima's stint in the Justice Department under former President Benigno Aquino.
Colanggo and two other witnesses testified that they delivered millions of pesos to De Lima or her staff, in return for political favors.
How did she react?
In a statement Tuesday, De Lima denounced the hearings as a "blatant exercise in harassment and persecution."
She condemned the disclosure of her cellphone number and home address, both of which were provided by witnesses as supposed proof that they knew her.
"(I have been) bombarded by text messages ... and phone calls from unknown persons, threatening me, harassing me, calling me the vilest of names," she said.
What about Duterte?
Speaking to supporters in Davao Tuesday, Duterte joked about the accusations against him.
"Yes, I kill, that's true, but not that many. 1700? Maybe more like 1,004," he said.
He said that when he was mayor, "it was very simple. I said get out of here -- if you're into drugs, murder for hire -- get out of here. This is true, I will kill you. And in the process I killed many upon my direction. There's no problem there."
So what happens now?
According to Pacquiao and new Human Rights Committee head Richard Gordon, the investigation into extrajudicial killings will proceed without De Lima.
He added that Matobato would be included in the next hearing, but would be asked only to testify on the recent spate of extrajudicial killings, not past incidents or allegations about the Davao Death Squad.
CNN's Kathy Quiano and journalist Charie Villa contributed reporting.